Equiptment and Techniques
We firmly believe that science is about sharing resources and knowledge! If you are interested in working with us or would like to get access to any of our equiptment please contact us. We are always happy to share our resources, give advise on behavioural testing, or start new colaborations.
Operant Boxes & Behavioural assessment
We have set up a bank of 8 modular operant chambers including a setup for optogenetic stimulation for the assessment of motor, cognitive and psychiatric phenotypes.
Inverted microscope: Leica DMI8
We have a Leica DMI8 inverted microscope fitted with cubes for Cy2, Cy3, and Cy5 and the following objectives: x5, x20 and x63. The microscope has an automated high precision stage and is great for overviews as well as close up pictures.
We have a blue and a yellow laser including a MASTER8 controller for optogenetic stimulation. The setup is movable and has been used with our operant boxes, freely moving recordings, electrochemistry in vivo and cell culture electrochemistry recordings.
We us carbon fiber electrods and/or microelectrode arrays to measurea analytes of interest in vitro and in vivo. IN our lab we have set up electrochemical detection for Dopamine, Glutamate, and GABA. Additional neurotransmitter systems that can be analysed but have not been used by our laboratory can be found here.
Electrochemistry allows for the sub-second recordings of neurotransmitters in acute and chronic recordings. Our system is fully optogenetics compatible and we can perform recordings in vitro, anaesthetised and freely moving rodents. Should you be iterested in using the equiptment, collaborations or want more information on the technology please contact us.
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