LUND UNIVERSITY, SWEDEN
This is an amazing time to conduct research in neuroscience. Novel technological breakthroughs allow for the manipulation of cell activity, the labelling neural networks, the visualisation of intricate details on a sub-cellular level, the recording of the neural code with high temporal resolution, the studying of gene expression profiles from single cells and even the manipulation of single genes themselves.
Only through studying how the brain works, and how behaviour and cognition arises from that neural code we will be able to understand ourselves as well as the working of brains that developed differently. The insights gained will enable us to treat diseases more efficiently in the future.
The overall aim of our research is to form causal relations between cell activity and behaviour. For that purpose we use technologies that allow for the reversible manipulation of cell activity (opto- and chemogenetics), technologies that allow for the recording of neurotransmitter release at sub-second resolution (amperometry and chronoamperometry), as well as complex and automated behavioural assessment that taps into motor and non-motor domains. We believe that a combination of these technologies will allow us to gain greater insight as well as to make treatments for neurodegenerative disorders safer and more efficient.
If you want to learn how to program you can sign up for our course: here.
The course is open to everyone but Lund University PhD students will be prioritized. No previous knowledge is required as this is for absolute beginners.
Our new BNL Journal Club format: Driver Seat Talks is now up and running. The first authors of a recent neuroscience paper will talk us through their manuscript with a personal account of how the story developed. Everybody is welcome to join. Currently we are scientists at all levels from 6 research groups from 4 countries, and growing.
For more info go to: www.driverseattalks.com
Paper accepted! Danish MSc work of using Machine Learning to detect and quantify microglia cells in rodent and NHP tissue is accepted in Plos One. Check our Techqniues page for links to the document and the code.
Papers have been accepted! Check out Brain Communications for a collaboration with the Canals Lab where our previous MSc student Naomi conducted some optogenetics/Echem.
Docentship approved :-)
Sene Gorgulu and Anastasiia Koval are starting in the lab. Welcome!
Our new Inscopix miniature microscopes have arrived :-) Happy Calcium imaging!!!!
Paper accepted! Francesco's work on motor and non-motor deficits in our AAV model is finally out in CRiN!
New MSc students start in the lab! Welcome Andreas and Teodor.
Grant support from MultiPark for our Symposium Brain Circuit Analysis! 3rd of May 2023!
Grant support from MultiPark for Innovation! Time to upgrade our ML system :-)
New infrastructure group: Brain Circuit Analysis funded with SEK 1 000 000 for in vivo calcium imaging.
Luis and Franceso got their methods paper accepted in JNM on automated quantification of axonal swellings! :-)
New paper accepted in Behavioural Brain Research! Congrats Francesco and all authors!
Febe and Irene joined BNL for a research internship. Welcome!!!
New paper accepted in JPD! Thanks to all collaborators for making this possible!
Today we visited the ProCivitas Highschool in Lund to talk about PD models, Stem cells and AAV vectors.
Francesco presented his work at the MultiPark lunchtime seminar series.
Very honoured to be the opponent of Martina Mazzocchi at Cork University for her PhD defense.
Francesco and Mati presented their research at the joined NECTA/ASNTR 2021 conference in Edinburgh
We are very greatful for continued funding support from the Parkinsonsfoundation for our research as well as two travel grants for Matilde and Francesco to present their data at the upcomming NECTAR meeting.
Diego Brignone has joined BNL to work with Matilde on gene therapy. Welcome Diego!
Chiara Venuti has joined BNL to work on AAV-aSyn induced pathology. Welcome Chiara!
Francesco has submitted his first manuscript! Fingers crossed!
Sarah Malandra has finished her research project with us . Thanks to the Ledrici foundation which enabled Sarah to investigate the dopamine release from dopaminergic grafts using optogenetics.
Great news, Iva has defended her MSc work at Rijeka University with 100/100! Congrats Iva!!!
The last student of this years' cohort has completed her MSc work. Good luck Iva!
Another one leaving :'-( Cecile has fined her internship. Good luck in Leuven Cecile.
Giovanna has finished her internship and is on her way back to Bari. Good luck Giovanna!
Our new book chapter on Electrochemical detection of Glutamate release is out!
Nuran has passed her MSc degree at Hasselt University with great distinction! Well done Nuran!
We are very greatful to the SLS for continued funding into our gene-therapy research!
Mati has passed her half-time examination! Thanks to the examiners Cilla Lundberg and Marco Ledri for a great discussion!
Sarah Malandra has joined BNL for a summer project on a scholarship by the Lerici foundation.
Klara has defended her BSc thesis this morning and has officially finished her research placement. Congrats Klara!
Its happening! Matilde has her date set for her PhD half-time: Join on zoom on 11th of June at 9:30am
Cecile Adant started her internship with us today. Welcome Cecile!
Greatful to receive grant support from the Hedlundsstiftelse :-)
Our new Journal Club website is up and running: www.driverseattalks.com.
Sad day for BNL, Ida has finished her internship and will be starting her PhD studies in Germany soon. All the best for your future Ida!
Presents have arrived: New DAPI cube and x10 objective have arrived from Leice :-) for our inverted microscope
Iva Pavicic has joined BNL for her MSc internship. Welcome Iva :-)
DIS student (virtual) visit. Great to have this interaction despite the pandemic. Francesco presented his work to students in Denmark and the USA.
Our coding club is growing up: we have now approval from the Faculty to run it as an official course for PhD students. Thanks to Anette and Tomas for the support and pushing at the Faculty!
Our perspectives article on the AAV-production has just been accepted in Neural Regeneration Research :-)
Klara Esbo started her BSc project in BNL. Welcome Klara!
Merry Christmas and happy holidays from BNL! Stay safe!
Giuseppe and David have successfully completed their projects. We wish them all the best for their future endeavours.
Our AAV-comparison paper is now online: https://www.nature.com/articles/s41598-020-78521-w :)
New paper from the group is finally accepted in Scientific Reports! Preprint will be available soon.
NECTAR 2020 Virtual Conference! Very happy to see old friends and mentors!
We are very greatful for support from the Royal Fysiographic Society in Lund.
Giovanna Cazzolla has started her MSc research internship with us today. Welcome Giovanna!
Ida Kulacz started her Erasmus+ internship with us today. Weclome Ida :-)
Our protocol on fast and reliable AAV-vector production is now online!
We are proud to announce that 6th grader Nayomi Shih from the Discovery Charter School has joined BNL as honorary lab member.
Great news, our methods paper on viral vector production is accepted. Stay tuned for the final product!!!!
Our new Leica Inverted DMi8 is up and running! Thanks Peter for an amazing service and the Crafoord foundation forthe funding!
Naomi King has completed her MSc project on optogenetics! Good luck back in the UK Naomi.
Giuseppe Tomasello joined BNL today for a 6 months master project. Welcome Giuseppe!
Anita Mehrdadian joined BNL today for a summer project. Welcome Anita!
Increadibly greatful for a grant by the Crafoordfoundation over SEK 452 660 for the purchase of a new inverted microscope.
Happy to see work we started in 2014 is finally published in Nature Communications!
Good news from Italy: Luca has graduated and is proudly wearing his laurels!
Coding club contiunes, now on zoom. Great way to push digitalization and happy to see thouse faces!
BNL is shutting down its activities for now. Students are home and only cruicial experimental timepoints will be carried out. Time for home-office and stay safe everybody.
New paper accepted: congrats Sophie and Gaynor for their work on mouse ES cells where we have contributed.
Excited to be part of UniStemDay 2020 again. Teachin highschool students about the work at BNL.
Welcome to our workshop!
Double birthday at BNL - Happy 21st Naomi and Swantje!
We are excited that Francesco Gubinelli started as a post doctoral researcher in our group. Welcome Francesco!
Today we welcome US american students from the DIS exchange program to the lab - looking forward to a great day!
Happy Palindrome Day!
Swantje Hauser started in the BNL today to work on her BSc project. Welcome Swantje.
And we are off for Christmas... Thanks to all collaborators and colleagues this year! We wish you all a merry christmas and a happy 2020!!!
BNL is now official member of MultiPark, a research network with great colleagues and facilities.
Andi is now officially on the NECTAR board.
And we are off to Cardiff! Looking forward to the NECTAR meeting for great science and discussions.
Thank you very much Royal Physiographic Society of Lund for supporting our research! The grant will be used for modelling cognitive symptoms in preclimical rodent modles of Parkinson's disease.
Very greatful to the Jeansonsstiftelsen for supporting our work!
Naomi King has joined us for a resarch project for her MSc degree :-) Welcome Naomi!
Last day of Summer (i.e. Semester kick-off) party at BMC B10. Beers & Burgers :-)
First publication where our lab is a major contributor: https://doi.org/10.1002/mds.27810. Congrats to Elena Espa and all co-authors!
Congratulations to Armelle and Tommie. Both obtained their MSc degree after their resarchinternship at BNL.
Congratulations to Manuela, she completed her Erasmus exchange and will start her PhD studies in Edinburgh soon.
Two Canadian medical students have joined the lab for a month of science! Welcome Christine and Celeste!
Summerparty at Skanör. Thanks Daniella for a great day at the beach and BBQ!
We are so greatful to the Crafoordska stiftelsen to support our research in mapping neuronal ensembles!
Honoured to be the opponent of Aiona Konomi from the Madsen Laboratory in CPH. Cograts on your MSc!!!
Very proud to welcome Barry Everitt to the lab!
We are very greatful to the Langmanska Stiftelsen for supporting our research on activity mapping!
Together with Daniella Rylander and Sophia Garde we are editing a special issue in Frontiers on:
Regeneration and Brain Repair. The special issue is now open for submissions.
Armelle Gensik has joined the BNL for her MSC project. Welcome Armelle!
Mikaela Johansson has started her MSc work in the BNL today. Welcome Mikaela!
Tommie Ros has started today on his MSc project. Welcome Tommie!
Manuela Rizzi has started today her MSc project with us! Welcome Manuela!
The Åhlenssiftelsen has generously granted us funds for a resarch project modelling cognitive deficits in preclinical rodent models of Parkinson's disease. Stort Tack!
The Ake Wiberg stiftelsen has granted us funding to study activity mapping of neuronal populations.
We are greatful for grant support from the Royal Physiographic Society of Lund to study neuronal ensembles.
Luca Cimino has joined us for his MSc project. Welcome to Sweden Luca!
Matilde Negrini is officially now a PhD student at Lund University!!!
Great day: Delivery of our operant boxes (#Segerfalkfoundation) and lasers for optogenetics :-)
We moved into our new labspace :-) Welcome at BMC B10 @Lund University.
We have recently published a book chapter on automated assessment of motor and non motor deficits: https://link.springer.com/protocol/10.1007%2F978-1-4939-7825-0_8.
We are greatful to the Crafoordska stiftelsen for funding our research on non-motor symptoms in a preclincal rodent model of PD.
The Segerfalk foundation has granted us SEK 135 000 for the purchachse of rat operant boxes.
Matilde Negrini started her human biology project in the group.
Wilson Stewart-Murray has joined from Keele University to conduct a research project for his MSc degree.